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Libido support

In stockPregnenolone
CompoundedPregnenoloneHormone precursor support for mood and energy
From$79/mo*
Get Started

* Capsule, in 3, 6 or 12 month plans. Prices may vary.

Compounded in the USAFSA and HSA eligiblePay over time withKlarnaAfterpayAffirm
  • Hormone precursor support for mood and energy
  • Same-day doctor visits and prescriptions
  • Free expedited shipping, all 50 states
  • No hidden fees, no surprise charges

Hormone precursor support for mood and energy

  • Pregnenolone, mood and energy
  • A 24/7 care team, day or night
  • Physician visits and follow-ups
  • Dose adjusted as you progress
  • Help with side effects
  • Medication from a US pharmacy
  • Free expedited shipping, all 50 states

You can cancel your treatment plan anytime from your online patient portal. There are no cancellation fees.

Note that canceling in the portal does not cancel any active orders already sent to the pharmacy. If your order is pending, contact us at [email protected] and we will help.

What would you like to feel?

Tap a goal to see the treatments built for it.

PT-141Matches your goal
Compounded
PT-141From $175/mo
Works onDesire, in the brain
TakenAbout 45 min before
FormInjection
Get started
Scream CreamMatches your goal
Compounded
Scream CreamFrom $99/mo
Works onArousal, where applied
TakenA few minutes before
FormCream
Get started
OxytocinMatches your goal
Compounded
OxytocinFrom $109/mo
Works onCloseness
TakenMelts under the tongue, daily
FormDissolving tablet
Get started
DHEAMatches your goal
Compounded
DHEAFrom $65/mo
Works onLibido and energy
TakenOne capsule each morning
FormCapsule
Get started
PregnenoloneMatches your goal
Compounded
PregnenoloneFrom $79/mo
Works onMood and energy
TakenOne capsule a day
FormCapsule
Get started

Personalized medicine,
in three simple steps

Submit your application
and meet with a doctor
Step1

Complete a quick form and meet a licensed provider 100% online. They'll see if a treatment plan is right for you.

Choosing what you are interested in on the Sipra intake
Get your medication
delivered at home
Step2

Once approved, your prescription ships directly to your door, fast and free.

Your Sipra box delivered to your door
Receive 24/7 support
and ongoing care
Step3

Regular check-ins and on-demand medical support to keep you on track.

24/7 support and ongoing care
sipra
Start here · one question
How long have you been experiencing menopause symptoms?
Tap an answer to start your hormone therapy intake. You can change it there.

More than a prescription

Most online programs ship a box. Sipra stays with you.

Sipra compared with a typical online program
sipraTypical online programs
No membership feeNo feeOften a monthly fee
The Sipra PromisePay only if a physician approves.$0 todayOften charged at checkout
Leave anytimeCancel online. No call, no form.AnytimeSteps may vary
One price, shipping includedVisits and support too.IncludedFees may vary
US-licensed pharmaciesURAC, ACHC and LegitScript accreditedAccreditedMay vary
Tested before it shipsPotency, plus sterility for injectionsYesTesting may vary
Dosing set by your physicianIncludedFollow-up may be limited
Side effect supportIncludedMay vary
Care team messaging, day or nightAnytimeHours may be limited
Start my visit

Nothing is charged until a physician approvesFSA and HSA eligible

Three places desire lives

Wanting, feeling and energy start in different places. That is why one treatment rarely fits everyone.

Body diagram
Desire, in the brainBrain

PT-141 acts on the brain’s desire signals. Oxytocin supports closeness.

Energy, from the adrenalsAdrenals

DHEA and pregnenolone are building blocks your body turns into hormones.

Arousal, where you feel itPelvis

A topical cream works on blood flow and sensation, right where it is applied.

Heard from our members

Real members, in their own words, on what changed after their first visit.

I stopped calling it a character flaw.

My relationship was good, but I didn’t feel like myself when it came to intimacy. I kept wondering what was wrong with me. Answering privately helped me say what I’d struggled to say out loud. The doctor took it seriously as a health concern. I didn’t feel judged, and I left feeling much less alone.

Nicole P. · FloridaTreated with Oxytocin
Verified member

Desire was a real health question.

I thought I was supposed to just accept it. The doctor asked about sleep, stress, my cycle and my relationship, and treated low desire as something worth looking into.

Amanda C. · GeorgiaTreated with PT-141
Verified member

She asked what I wanted, not what I should want.

I didn’t want someone deciding what normal is for me. The doctor started by asking what I hoped would feel different, and we built from there.

Jessica W. · IllinoisTreated with Scream Cream
Verified member

Menopause changed things. Someone noticed.

I had no words for how intimacy had changed after menopause. The questions named things I hadn’t said out loud, and the doctor explained how hormones play into it.

Diane K. · FloridaTreated with DHEA
Verified member

I could be honest at home.

Typing my answers privately made it easier to tell the truth. In a room, I would have said everything was fine.

Sofia R. · ArizonaTreated with Oxytocin
Verified member

The how and when were explained.

I had questions about timing and what to expect the first time. The doctor walked me through it step by step and said to message if anything felt off.

Brittany L. · OhioTreated with Scream Cream
Verified member

No one made it weird.

I was ready to feel embarrassed. Instead the whole thing felt calm and clinical in the best way. The doctor was warm and straightforward.

Megan T. · TennesseeTreated with PT-141
Verified member

We looked at the whole picture.

I mentioned my antidepressant almost as an afterthought. The doctor took it seriously and explained how it might be connected. That changed the conversation completely.

Rachel G. · VirginiaTreated with Pregnenolone
Verified member

My questions didn’t feel silly.

I had a long list. The doctor answered every one, including the ones I almost deleted before sending.

Christine P. · WisconsinTreated with Oxytocin
Verified member

I knew who to ask afterward.

Having a place to send questions between visits made me feel looked after. The replies were quick and personal.

Natalie H. · ColoradoTreated with DHEA
Verified member

The pharmacy behind your treatment

Licensed 503A pharmacy

Your treatment ships to all 50 states

Compounded in the USA

Made for you, never mass-produced

Tested before it ships

Sterility, endotoxin, and potency, under USP 795 and 797

Independently accredited

URAC, ACHC, and LegitScript

From your visit to your door

Exactly what happens after your visit, who handles it, and when you pay. Nothing is charged until a physician approves.

Start my visit
  1. 01Online visit

    A few questions, no charge

  2. 02Physician review

    A licensed US physician

  3. 03Approval

    Charged only if approved

  4. 04Pharmacy

    Prepared in the US

  5. 05Delivery

    Expedited shipping included

  6. 06Ongoing care

    Check-ins and dose changes

Dr. Jillian Foglesong Stabile, Sipra Medical Reviewer
Sipra Medical Reviewer

“Desire and arousal are health topics, not personal failings. What matters is naming what feels different to you, then choosing care that matches it.”

Dr. Jillian Foglesong StabileMD, FAAFP, DABOM

Board-certified family physician and Diplomate of the American Board of Obesity Medicine.

American Board of Family Medicine
American Board of Obesity Medicine
Wake Forest University School of Medicine

Sexual wellness questions, answered

It covers low desire, trouble with arousal, and changes in sensation that can come with hormones, stress, or life stage. A licensed US physician reviews your online intake and recommends options that fit your history. It is not one pill for everyone.

PT-141, also called bremelanotide, acts on pathways in the brain tied to sexual desire. It is taken as needed rather than every day. It is compounded, which means it is not FDA-approved, and your physician decides if it is right for you.

Oxytocin is a hormone linked to bonding and arousal. DHEA and pregnenolone are hormones your body makes, and their levels tend to fall with age. Scream Cream is a topical blend applied to the area to support sensation. Your physician decides which, if any, fit you.

It depends on the option. Topicals and as-needed medications may act within a short window, while hormone support can take weeks. Individual results vary.

PT-141 can cause nausea, flushing, headache, and a short rise in blood pressure. DHEA can cause acne, oily skin, or unwanted hair growth. Topicals can cause local irritation, so tell your care team about anything new.

PT-141 is not for women with uncontrolled high blood pressure or heart disease. Hormone-based options may not suit women with certain cancers or who are pregnant or breastfeeding. Your physician reviews your full history first.

A compounded medication is prepared by a licensed pharmacy for a specific patient. Compounded medications are not FDA-approved, and they are not the same as any brand-name product. Your plan shows what you receive, and it ships from a licensed US 503A pharmacy that tests it first.

No office visit is needed. A licensed US physician reviews your online intake, and may suggest labs if hormones could be part of the picture. Your care team helps you through that step.

Plans are billed per plan term, and the price does not change with your dose. Shipping is included, and you pay nothing unless a physician approves your treatment. It is cash pay with no insurance needed, and FSA and HSA funds can be used.

Yes. You can cancel online at any time, with no phone call and no form. If something is not working, message your care team and your physician can adjust your plan.

Your hormones deserve better than guesswork

  • Online visits with licensed physicians
  • Estradiol, progesterone, HRT & sexual wellness
  • Lab panels at member pricing
  • FSA & HSA eligible with all plans
A smiling woman with dark hair in a cream sweater
From$65/mo

From price shown is the 12-month plan rate. Prices may vary.