Do I need a letter of medical necessity to use HSA funds for semaglutide?
A prescription medication and a weight-loss program can have different documentation requirements. Ask your HSA custodian or FSA administrator what it requires for the exact expense. A letter of medical necessity is not automatically required for every semaglutide prescription. 1, 2

IRS guidance generally recognizes prescribed medicines as medical expenses. Weight-loss services and program fees require closer attention to their medical purpose and the applicable tax rules.
A payment card accepting the charge is not final proof of eligibility. Keep the prescription, itemized receipt, and any documentation requested by the administrator.
When might a letter be requested?
An administrator may request medical-necessity documentation for a program or service whose eligibility is unclear. Ask for its written requirements before paying, including who must provide the letter.
Can one letter make every membership charge eligible?
No. Charges should be separated into their actual services. General wellness, food, or other nonqualifying expenses do not become eligible simply because they appear in a medical program.

Bottom line
Clarify the expense and the documentation first. A prescription receipt and a medical-necessity letter serve different purposes.
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- Same-day doctor visits and prescriptions
- Semaglutide, tirzepatide & other GLP-1s
- FSA & HSA eligible with all plans

From price shown is the 12-month plan rate. Prices may vary.
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