TSH test, explained.
A TSH test measures thyroid stimulating hormone, the signal your pituitary gland sends to tell your thyroid how much hormone to make. TSH usually rises when the thyroid is underactive and falls when it is overactive. Many labs use an adult range of about 0.4 to 4.5 mIU/L, and your report prints its own.
- What it measures
- The signal that tells your thyroid how hard to work
- Fasting
- Not needed. Ask about pausing biotin first
- Who should test
- Adults with symptoms or risk factors
- In Lab Pass
- Yes, every plan, $199 a year
TSH ranges
| Result | TSH |
|---|---|
| Common lab range | About 0.4 to 4.5 mIU/L |
| US reference population (NHANES III) | 0.45 to 4.12 mIU/L |
Sources: AACE and ATA hypothyroidism guideline (2012), which advises using each lab's own range, and the NHANES III population data. TSH often runs higher with age and differs in pregnancy; your report prints its own range.
Who should test
The USPSTF found too little evidence to recommend for or against TSH screening in adults without symptoms. Thyroid guidelines favor testing when there is a reason to look: symptoms, another autoimmune condition such as type 1 diabetes, a past thyroid problem or neck radiation, a family history of thyroid disease, or medicines such as amiodarone or lithium.
What can throw it off
Biotin, common in hair, skin and nail supplements, can throw off thyroid results, and many labs ask you to stop it at least 72 hours before the draw. TSH also runs higher at night and early morning, and can shift with a recent illness, steroids, pregnancy, older age, or a change in thyroid medicine in the last 6 to 8 weeks. Check with your clinician before stopping any supplement or medicine.
How Sipra reads it
Your Lab Pass reads TSH on its range with a plain language read. For more than TSH, the Thyroid Deep-Dive adds the full thyroid hormone and antibody picture for $69 in most states.
Questions, answered
Other tests in Lab Pass
General information, not medical advice. A licensed physician signs your lab order; talk with your own clinician about what a result means for you.